Simplex on 2M can be a lot of fun. If you haven't tried it in a while, you should. You might be surprised by some of the distances you can communicate directly without a repeater.
146.52 Mhz the National 2M calling frequency is the place to start. I monitor it on a scanner and have been surprised how often you will hear someone these days. Since the Pandemic started last year, there seems to be many more folks on the air, so give it a try. If you are using any of the digital voice modes (D-Star, Fusion, P25, NXDN), consider starting on 146.52 and then moving to an alternate frequency (like 146.535, 146.550 , 146.565 and 146.580 Mhz) out of courtesy to others who might only have analog capabilities.
Also, in Central NY there is a Simplex net held twice a month. Check it out:
CNY (Syracuse) 2m Simplex Night – Net Control: Larry Rausch KD2MTG
7pm on the 1st and 3rd Thursday of every month (with exception to holidays)
146.580 Mhz Primary.
Conceptual Local Cross Band Repeat system set up on 446.600 Mhz (NO PL) for stations to try if location / propagation presents difficulties.